Human Baff Elisa Kit

Description: For quantitative detection of human BAFF in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Description: Enzyme-linked immunosorbent assay kit for quantification of Human BAFF in samples from serum, plasma, tissue homogenates and other biological fluids.

Description: Description of target: BAFF was regularly detected by enzyme-linked immunosorbent assay in brain tissue lysates and in normal spinal fluid, and in astrocytes by double fluorescence microscopy. BAFF was localized in astrocytes close to BAFF-R-expressing immune cells. BAFF receptors were strongly expressed in situ in primary central nervous system (CNS) lymphomas.1 The TNF superfamily member B cell-activating factor (BAFF) plays an important role in humoral immunity and in autoimmune diseases, including RA.Local BAFF gene targeting inhibited proinflammatory cytokine expression, suppressed generation of plasma cells and Th17 cells, and markedly ameliorated joint pathology.2 The B cell activating factor BAFF (BlyS/TALL-1/zTNF4) is a tumor necrosis factor (TNF)-related ligand that promotes B cell survival and binds to three receptors (BCMA, TACI, and the recently described BAFF-R).3 Human BAFF was mapped to chromosome 13q32-34.4 The standard used in this kit is recombinant soluble human BAFF (A134-L295) with the molecular mass of 19.6KDa.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 2 pg/ml

Description: ELISA kit for detection of BAFF in the research laboratory